In contrast to other sensory systems, the olfactory system is already fully mature at birth, controlling mother-offspring interactions and neonatal survival.
Perturbation of developmental processes of prefrontal layer II/III pyramidal neurons is sufficient to diminish prefrontal-hippocampal coupling and impairs cognitive performance throughout development.
We a very proud of our college Sebastian Bitzenhofer who got awarded with the PhD price from the Freundes- und Förderkreis des UKE e.V.. Congratulations Sebastian! [link]
Optogenetic approaches offer huge advantages in spatial, temporal and cell-type specific control of neuronal activity
Fetal brain development is pivotally dependent on environmental triggers in utero.
We show that reciprocal connectivity between OB and LEC is present at neonatal age and a continuous slow respiration-related rhythm and discontinuous theta bursts characterize the activity in the neonatal OB.
We compare the dorsal and ventral/medial portions of the developing hippocampus (mice of 8-10 days of age) and show that:
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Modulation of firing rates and timing of firing are key mechanisms of multisensory processing in directly connected primary sensory cortices.
Optogenetic manipulations increased the understanding of neuronal network activity in the adult brain […]