How the sense of smell influences cognition throughout life, Kostka JK & Bitzenhofer SH (2022). Neuroforum

Generation and propagation of network bursts in the basal ganglia exhibit dynamic changes during early postnatal development, Klavinskis-Whiting S, Bitzenhofer SH, Hanganu-Opatz IL, Ellender T (2022). biorxiv

An increase of inhibition drives the developmental decorrelation of neural activity, Chini M, Pfeffer T, Hanganu-Opatz IL (2022).eLife

Pregnancy-induced maternal microchimerism shapes neurodevelopment and behavior in mice, Schepanski S, Chini M, Sternemann V, Urbschat C, Thiele K, Sun T, Zhao Y, Woestemeier A, Thieme M, Zazara D, Alawi M, Fischer N, Heeren J, Vladimorov N, Woehler A, Puelles V, Bonn S, Gagliani N, Hanganu-Opatz IL, Arck P (2022). Nat Commun.

Calcium Imaging and Electrophysiology of hippocampal Activity under Anesthesia and natural Sleep in Mice, Formozov A, Chini M, Dieter A, Yang W, Pöpplau, J A, Hanganu-Opatz IL, Wiegert S (2022). Sci Data

Postnatal Development of Centrifugal Inputs to the Olfactory Bulb, Kostka J K, Bitzenhofer S (2022). Front. Neuroscience

Sparser and Less Efficient Hippocampal-Prefrontal Projections account for Developmental Network Dysfunction in a Model of Psychiatric Risk Mediated by Gene-Environment Interaction, Song L, Xu X, Putthoff P, Fleck D, Spehr M, Hanganu-Opatz IL (2022). J Neurosci

TAOK2 rescues autism-linked developmental deficits in a 16p11.2 microdeletion mouse model 
, Scharrenberg R, Richter M, Johanns O, Meka DP, Rücker T, Murtaza N, Lindenmaier Z, Ellegood J, Naumann A, Zhao B, Schwanke B, Sedlacik J, Fiehler J, Hanganu-Opatz IL, Lerch JP ,Singh KK & Calderon de Anda F (2022). Mol Psychiatry

Developmental decrease of entorhinal-hippocampal communication in immune-challenged DISC1 knockdown mice, Xu X, Song L, Kringel R & Hanganu-Opatz IL (2021). Nat Commun.

Prefrontal Cortex Development in Health and Disease: Lessons from Rodents and Humans, Chini M, Hanganu-Opatz IL (2021). Trends NeuroSci

Knock-Down of Hippocampal DISC1 in Immune-Challenged Mice Impairs the Prefrontal-Hippocampal Coupling and the Cognitive Performance Throughout Development, Xu X, Song L, Hanganu-Opatz IL (2021). Cereb Cortex

Olfactory-driven beta band entrainment of limbic circuitry during neonatal development
Kostka, Johanna K. & Hanganu-Opatz, I.L. (2021). bioRxiv

Anesthetics fragment hippocampal network activity, alter spine dynamics, and affect memory consolidation.
Yang, W., Chini, M., Pöpplau, J. A., Formozov, A., Dieter, A., Piechocinski, P., … & Wiegert, J. S. (2021). PLoS biology, 19(4), e3001146.

Transient developmental increase of prefrontal activity alters network maturation and causes cognitive dysfunction in adult mice.
Bitzenhofer, S. H., Poepplau, J. A., Chini, M., Marquardt, A., & Hanganu-Opatz, I. L. (2021). Neuron, 109(8), 1350-1364.

The Logic of Developing Neocortical Circuits in Health and Disease
Hanganu-Opatz, I. L., Butt, S. J., Hippenmeyer, S., García, N. V. D. M., Cardin, J. A., Voytek, B., & Muotri, A. R. (2021). Journal of Neuroscience.

Prefrontal Cortex Development in Health and Disease: Lessons from Rodents and Humans
Chini, M. & Hanganu-Opatz, I. L. (2020). Trends in Neurosciences

Gamma activity accelerates during prefrontal development
Bitzenhofer, S. H., Poepplau, J. A., & Hanganu-Opatz, I. L. (2020). Elife

Bursting mitral cells time the oscillatory coupling between olfactory bulb and entorhinal networks in neonatal mice
Kostka, J.K., Gretenkord S. & Hanganu-Opatz, I.L. (2020). J Physiol.

Knock-Down of Hippocampal DISC1 in Immune-Challenged Mice Impairs the Prefrontal–Hippocampal Coupling and the Cognitive Performance Throughout Development
Xu, X., Song, L. & Hanganu-Opatz, I.L. (2020). Cerebral Cortex

Anesthetics uniquely decorrelate hippocampal network activity, alter spine dynamics and affect memory consolidation
Yang, W., Chini, M., Poepplau, J. A., Formozov, A., Piechocinski, P., Rais, C., Morellini, F., Sporns, O., Hanganu-Opatz, I. L., Wiegert, J. S. (2020). bioRxiv.

Synchronous infra-slow oscillations organize ensembles of accessory olfactory bulb projection neurons into distinct microcircuits
Tsitoura, C., Malinowski, S., Mohrhardt, J., Degen, R., DiBenedictis, B. T., Gao, Y., Watznauer, K., Gerhold, K., Nagel, M., Weber, M.,  Rothermel, M., Hanganu-Opatz, I.L., Ben-Shaul Y., Davison, I. & Spehr, M. (2020).  Journal of Neuroscience.

Cross-Talk of Low-Level Sensory and High-Level Cognitive Processing: Development, Mechanisms, and Relevance for Cross-Modal Abilities of the Brain
Xu, X., Hanganu-Opatz, I., & Bieler, M. (2020). Frontiers in Neurorobotics

Early postnatal inhibitory circuit development in the mouse medial prefrontal and primary somatosensory cortex
Kalemaki K., Xu X.,  Hanganu-Opatz I. L., Sidiropoulou K. and Karagogeos D. (2020) bioRxiv, doi: https://doi.org/10.1101/2020.01.21.913913

Resolving and Rescuing Developmental Miswiring in a Mouse Model of Cognitive Impairment
Mattia Chini, Jastyn A. Pöpplau, Christoph Lindemann, Laura Carol-Perdiguer, Marilena Hnida, Victoria Oberländer, Xiaxia Xu, Joachim Ahlbeck, Sebastian H. Bitzenhofer, Christoph Mulert, Ileana L. Hanganu-Opatz (2020), Neuron

Tapered fibers combined with a multi-electrode array for optogenetics in mouse medial prefrontal cortex.

Sileo L., Bitzenhofer S., Spagnolo B., Poepplau J., Holzhammer T., Pisanello M., Pisano F., Bellistri E., Maglie E., Ruther P, Hanganu Opatz I. L., De Vittorio M., Pisanello F. (2018).  Frontiers in Neuroscience, 12, 771.

Multisensory integration in rodent tactile but not visual thalamus

Bieler B., Xu X., Marquardt A. & Hanganu-Opatz I.L. (2018). Scientific Reportsvolume 8, Article number: 15684 (2018)

Prenatal Immune and Endocrine Modulators of Offspring’s Brain Development and Cognitive Functions Later in Life

Schepanski, S., Buss, C.,  Hanganu-Opatz, I.L., & Arck, P. C. (2018). Prenatal immune and endocrine modulators of offspring’s brain development and cognitive functions later in life. Frontiers in Immunology, 9, 2186.

Altered TAOK2 activity causes autism-related neurodevelopmental and cognitive abnormalities through RhoA signaling 

Richter, M., Murtaza, N., Scharrenberg, R., White, S. H., Johanns, O., Walker, S., Yuen, R., Schwanke, B., Bedürftig, B., Henis, M., Scharf, S., Kraus, V., Dörk, R., Hellmann, J., Lindenmaier, Z., Ellegood, J., Hartung, H., Kwan, V., Sedlacik, J., Fiehler, J., Schweizer, M., Lerch, J. P., Hanganu-Opatz, I. L.,Morellini, F., Scherer, S. W., Singh, K. K., Calderon de Anda, F. (2018). Altered TAOK2 activity causes autism-related neurodevelopmental and cognitive abnormalities through RhoA signaling. Molecular psychiatry, 1.

Glutamatergic drive along the septo-temporal axis of hippocampus boosts prelimbic oscillations in the neonatal mouse 

Ahlbeck J, Song L, Chini M, Bitzenhofer SH, Hanganu-Opatz IL. Bartos M, ed. eLife. 2018;7:e33158. doi:10.7554/eLife.33158.

Methodological Approach for Optogenetic Manipulation of Neonatal Neuronal Networks
Bitzenhofer, SH., Ahlbeck J, Hanganu-Opatz IL. Frontiers in Cellular Neuroscience 11 (2017): 239. PMC. Web. 17 Oct. 2017. 

Rate and Temporal Coding Convey Multisensory Information in Primary Sensory Cortices
Bieler M, Cichon N, Schildt S, Röder B, Hanganu-Opatz I
eNeuro. 2017;4(2).

Visual-tactile processing in primary somatosensory cortex emerges before cross-modal experience
Bieler M, Sieben K, Schildt S, Röder B, Hanganu-Opatz I
SYNAPSE. 2017;71:6.

Layer-specific optogenetic activation of pyramidal neurons causes beta-gamma entrainment of neonatal networks
Bitzenhofer S, Ahlbeck J, Wolff A, Wiegert J, Gee C, Oertner T, Hanganu-Opatz I
NAT COMMUN. 2017;8:14563.

Neocortical Layer 6B as a Remnant of the Subplate – A Morphological Comparison
Marx M, Qi G, Hanganu-Opatz I, Kilb W, Luhmann H, Feldmeyer D
CEREB CORTEX. 2017;27(2):1011-1026.

Early-life stress impairs recognition memory and perturbs the functional maturation of prefrontal-hippocampal-perirhinal networks
Reincke S, Hanganu-Opatz I
SCI REP-UK. 2017;7:42042.

Glutamatergic deficit and schizophrenia-like negative symptoms: new evidence from ketamine-induced mismatch negativity alterations in healthy male humans
Thiebes S, Leicht G, Curic S, Steinmann S, Polomac N, Andreou C, Eichler I, Eichler L, Zöllner C, Gallinat J, Hanganu-Opatz I, Mulert C
J PSYCHIATR NEUROSCI. 2017;42(4):273-283.

Interdependent Conductances Drive Infraslow Intrinsic Rhythmogenesis in a Subset of Accessory Olfactory Bulb Projection Neurons
Gorin M, Tsitoura C, Kahan A, Watznauer K, Drose D, Arts M, Mathar R, O’Connor S, Hanganu-Opatz I, Ben-Shaul Y, Spehr M
J NEUROSCI. 2016;36(11):3127-44.

Thalamic and Entorhinal Network Activity Differently Modulates the Functional Development of Prefrontal-Hippocampal Interactions
Hartung H, Brockmann M, Pöschel B, De Feo V, Hanganu-Opatz I
J NEUROSCI. 2016;36(13):3676-90.

From Shortage to Surge: A Developmental Switch in Hippocampal-Prefrontal Coupling in a Gene-Environment Model of Neuropsychiatric Disorders
Hartung H, Cichon N, De Feo V, Riemann S, Schildt S, Lindemann C, Mulert C, Gogos J, Hanganu-Opatz I
CEREB CORTEX. 2016;26(11):4265-4281.

Spindle Activity Orchestrates Plasticity during Development and Sleep
Lindemann C, Ahlbeck J, Bitzenhofer S, Hanganu-Opatz I
NEURAL PLAST. 2016;5787423.

Balancing family with a successful career in neuroscience
Poirazi P, Belin D, Gräff J, Hanganu-Opatz I, López-Bendito G
EUR J NEUROSCI. 2016;44(2):1797-803.

The road to independence. How to get funding in neuroscience
Yaksi E, Poirazi P, Hanganu-Opatz I
EUR J NEUROSCI. 2016;43(5):603-7.

Resting-state theta-band connectivity and verbal memory in schizophrenia and in the high-risk state
Andreou C, Leicht G, Nolte G, Polomac N, Moritz S, Karow A, Hanganu-Opatz I, Engel A, Mulert C
SCHIZOPHR RES. 2015;161(2-3):299-307.

Increased Resting-State Gamma-Band Connectivity in First-Episode Schizophrenia
Andreou C, Nolte G, Leicht G, Polomac N, Hanganu-Opatz I, Lambert M, Engel A, Mulert C
SCHIZOPHRENIA BULL. 2015;41(4):930-939.

Oscillatory activity in developing prefrontal networks results from theta-gamma-modulated synaptic inputs.
Bitzenhofer S, Sieben K, Spehr M, Hanganu-Opatz I
CELL REP. 2015;11(3):486-497.

Neonatal hypoxia-ischemia impairs juvenile recognition memory by disrupting the maturation of prefrontal-hippocampal networks
Domnick N, Gretenkord S, De Feo V, Sedlacik J, Brockmann M, Hanganu-Opatz I
EXP NEUROL. 2015;273:202-14.

Introduction to the Special Issue on Multisensory Development and Plasticity
Gori M, Hanganu-Opatz I
MULTISENS RES. 2015;28(1-2):31-32.

You are not alone: selecting your group members and leading an outstanding research team
Hanganu-Opatz I, Mameli M, Káradóttir R, Spires-Jones T
EUR J NEUROSCI. 2015;42(12):3012-7.

Unraveling Cross-Modal Development in Animals: Neural Substrate, Functional Coding and Behavioral Readout
Hanganu-Opatz I, Rowland B, Bieler M, Sieben K
MULTISENS RES. 2015;28(1-2):33-69.

Event-related potential evidence for a dynamic (re-)weighting of somatotopic and external coordinates of touch during visual-tactile interactions
Ley P, Steinberg U, Hanganu-Opatz I, Röder B
EUR J NEUROSCI. 2015;41(11):1466-74.

Treatment during a vulnerable developmental period rescues a genetic epilepsy
Marguet S, Le-Schulte V, Merseburg A, Neu A, Eichler R, Jakovcevski I, Ivanov A, Hanganu-Opatz I, Bernard C, Morellini F, Isbrandt D
NAT MED. 2015;21(12):1436-44.

Neonatal Restriction of Tactile Inputs Leads to Long-Lasting Impairments of Cross-Modal Processing
Sieben K, Bieler M, Röder B, Hanganu-Opatz I
PLOS BIOL. 2015;13(11):Art. e1002304.

Resting-state connectivity in the prodromal phase of schizophrenia: insights from EEG microstates
Andreou C, Faber P, Leicht G, Schoettle D, Polomac N, Hanganu-Opatz I, Lehmann D, Mulert C
SCHIZOPHR RES. 2014;152(2-3):513-20.

Oscillatory coupling within neonatal prefrontal-hippocampal networks is independent of selective removal of GABAergic neurons in the hippocampus
Bitzenhofer S, Hanganu-Opatz I
NEUROPHARMACOLOGY. 2014;77:57-67.

Activation of glycine receptors modulates spontaneous epileptiform activity in the immature rat hippocampus
Chen R, Okabe A, Sun H, Sharopov S, Hanganu-Opatz I, Kolbaev S, Fukuda A, Luhmann H, Kilb W
J PHYSIOL-LONDON. 2014;592(Pt 10):2153-68.

Unsupervised classification of neocortical activity patterns in neonatal and pre-juvenile rodents
Cichon N, Denker M, Grün S, Hanganu-Opatz I
FRONT NEURAL CIRCUIT. 2014;8:50.

Hypoxia-ischemia disrupts directed interactions within neonatal prefrontal-hippocampal networks
Brockmann M, Kukovic M, Schönfeld M, Sedlacik J, Hanganu-Opatz I
PLOS ONE. 2013;8(12):e83074.

Neonatal cholinergic lesion alters the acoustic structure of infant rat vocalization but not the early cognitive development.
Krüger H, Hanganu-Opatz I
DEV PSYCHOBIOL. 2013;55(3):294-308.

Oscillatory entrainment of primary somatosensory cortex encodes visual control of tactile processing.
Sieben K, Röder B, Hanganu-Opatz I
J NEUROSCI. 2013;33(13):5736-5749.

Cholinergic control in developing prefrontal-hippocampal networks.
Janiesch P, Krüger H, Pöschel B, Hanganu-Opatz I
J NEUROSCI. 2012;31(49):17955-17970.

Neonatal hippocampal lesion alters the functional maturation of the prefrontal cortex and the early cognitive development in pre-juvenile rats.
Krüger H, Brockmann M, Salamon J, Ittrich H, Hanganu-Opatz I
NEUROBIOL LEARN MEM. 2012;97(4):470-481.

Coupled oscillations mediate directed interactions between prefrontal cortex and hippocampus of the neonatal rat.
Brockmann M, Pöschel B, Cichon N, Hanganu-Opatz I
NEURON. 2011;71(2):332-347.

Between molecules and experience: role of early patterns of coordinated activity for the development of cortical maps and sensory abilities.
Hanganu-Opatz I, Ileana L
BRAIN RES REV. 2010;64(1):160-176.

Subplate cells: amplifiers of neuronal activity in the developing cerebral cortex.
Luhmann H, Kilb W, Hanganu-Opatz I
FRONT NEUROANAT. 2009;3:19.

Three patterns of oscillatory activity differentially synchronize developing neocortical networks in vivo.
Yang J, Hanganu-Opatz I, Sun J, Luhmann H
J NEUROSCI. 2009;29(28):9011-9025.