Check out our latest publication in The Journal of Physiology by Kostka and Hanganu-Opatz. We show that early activity in the olfactory bulb (OB) of neonatal mice, synchronizes the limbic circuity in the beta frequency range. Moreover, it drives neuronal and network activity in lateral enthorinal cortex (LEC), as well as subsequently, hippocampus (HP) and prefrontal cortex via long-range projections from mitral cells to HP-projecting LEC neurons. Thus, OB activity shapes the communication within limbic circuits during neonatal development.

Olfactory-driven beta band entrainment of limbic circuitry during neonatal development, Kostka JK & Hanganu-Opatz IL (2023). The Journal of Physiology

image