A big shout out to Luna Jammal Salameh and Veronica Egger, who led this study, from University Regensburg. We show that heartbeat-induced pressure waves directly modulate the firing of a subset of neurons in the olfactory bulb (and other areas). These neurons increase their firing rate within ~20 ms after heartbeats, mediated by fast mechanosensitive […]
In neonatal rodents, olfaction is already functional and more mature than the other senses. By silencing the outputs of olfactory bulb in the early postnatal days of mice, we found that the transient suppression of olfactory output led to a long-lasting reduction of oscillatory coupling in the downstream entorhinal-hippocampal networks and poor performance in cognitive […]
Check out our newest publication in the Journal of Physiology by Kostka & Hanganu-Opatz. We show that the neonatal olfactory bulb (OB) synchronizes the limbic circuity in the beta frequency range. Moreover, it drives neuronal and network activity in the lateral entorhinal cortex (LEC), as well as subsequently, hippocampus (HP) and prefrontal cortex (PFC) via […]
Check out our latest publication in The Journal of Physiology by Kostka and Hanganu-Opatz. We show that early activity in the olfactory bulb (OB) of neonatal mice, synchronizes the limbic circuity in the beta frequency range. Moreover, it drives neuronal and network activity in lateral enthorinal cortex (LEC), as well as subsequently, hippocampus (HP) and […]
Sebastian received the Du Bois-Reymond Prize of the German Physiological Society.
Steven and his colleagues investigated the molecular and cellular characteristics of maternal cells (short: MMc) that are transferred to the fetus during pregnancy. We showed that MMc seed the developing brain and influence the oscillatory entrainment of prefrontal-hippocampal circuits by altering microglia-induced synapse elimination. By this pathway, maternal cells contribute to the development of behavioral […]
She’s looking forward to work in Sebastians Team „Cognitive Olfaction“ to investigate how the propagation of odor-evoked activity is altered in a mouse model for mental disorders. Welcome Fiona!
Johanna and Sebastian are happy to announce the new paper: “Postnatal Development of Centrifugal Inputs to the Olfactory Bulb”. Johanna K. Kostka and Sebastian H. Bitzenhofer