While sensory perception and cognitive processing represent constant research topics in Neuroscience, they have seldom been investigated synergistically. This is especially true when considering their ontogeny. The largely separate investigation of sensory and cognitive ontogeny stems from the fact that most sensory systems are underdeveloped during early life and, thus, their impact on the formation of neuronal networks underlying cognitive processing has been deemed negligible. As a notable exception, the olfactory system reaches full maturity during intrauterine life, controlling mother-offspring interactions and survival. We investigate the structural and functional principles underlying the connectivity and communication between the olfactory bulb and the memory-relevant limbic circuitry during neonatal and juvenile development.
Kostka J.K., Gretenkord S. & Bursting mitral cells time the oscillatory coupling between olfactory bulb and entorhinal networks in neonatal mice. The Journal of Physiology, 598(24), 5753-5769.
Gretenkord S., Kostka J. K., Hartung H., Watznauer K., Fleck D., Minier-Toribio A., Spehr M., Hanganu-Opatz I. L. (2019). Coordinated electrical activity in the olfactory bulb gates the oscillatory entrainment of entorhinal networks in neonatal mice. PLOS Biology 17(1): e2006994