Congratulation to Steven to the new publication in Nature Communications!

Steven and his colleagues investigated the molecular and cellular characteristics of maternal cells (short: MMc) that are transferred to the fetus during pregnancy. We showed that MMc seed the developing brain and influence the oscillatory entrainment of prefrontal-hippocampal circuits by altering microglia-induced synapse elimination. By this pathway, maternal cells contribute to the development of behavioral abilities in neonatal and pre-juvenile offspring.

In this image, maternal microchimeric cells (MMc) were detected and located by the expression of tdTomato-fluorescence
in the developing brain (E18.5) of a non-expressing offspring.

Follow the link to the paper…